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Article

The Commercial Antibodies Widely Used to Measure H3 K56 Acetylation Are Non-Specific in Human and Drosophila Cells.

PloS one - 1 Jan 2016

Pal Sangita, Graves Hillary, Ohsawa Ryosuke, Huang Ting-Hsiang, Wang Pingping, Harmacek Laura, Tyler Jessica

Abstract excerpt

Much of our understanding of the function of histone post-translational modifications in metazoans is inferred from their genomic localization and / or extrapolated from yeast studies. For example, acetylation of histone H3 lysine 56 (H3 K56Ac) is assumed to be important for transcriptional regulation in metazoan cells based on its occurrence at promoters and its function in yeast. Here we directly assess the...

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Identifiers

PMID: 27187594
DOI: 10.1371/journal.pone.0155409
PMCID: PMC4871326

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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