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Article

Global regulation of Hox gene expression in C. elegans by a SAM domain protein.

Developmental cell - 1 Jun 2003

Zhang Hong, Azevedo Ricardo B R, Lints Robyn, Doyle Christina, Teng Yingqi, Haber Daniel, Emmons Scott W

Abstract excerpt

Polycomb group (PcG)-mediated repression of C. elegans Hox genes has not been demonstrated, and genes homologous to components of one of the PcG complexes (PRC1) have not been identified in the C. elegans genome. We find that a mechanism of general Hox gene repression exists in C. elegans, carried out in part by SOP-2, a protein related to, but not orthologous with, any PcG protein. sop-2 mutations lead to...

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Source

Identifiers

PMID: 12791274
DOI: 10.1016/s1534-5807(03)00136-9

Genes

PRC1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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