Article
Phenotypic characterization of antigenic hybrids of poliovirus.
Microbial pathogenesis - 1 Jan 1991
Murdin A D, Kameda A, Murray M G, Wimmer E
Abstract excerpt
Three poliovirus hybrids, modified in neutralization antigenic sites (NAgs) I or II, were characterized for several phenotypic traits. The modifications to the capsid interfered with some stage of the life-cycle of the virus, since all three hybrids were growth-impaired in comparison to polioviru...
Topics
- Amino Acid Sequence
- Antigens, Viral
- Capsid
- Chimera
- Molecular Sequence Data
- Neutralization Tests
- Phenotype
- Poliovirus
- Temperature
- Viral Plaque Assay
- Virus Replication