Article
[Antigen differences of genetic variants Abent+ and Abent- poliovirus vaccine strain of III type].
Mikrobiolohichnyi zhurnal (Kiev, Ukraine : 1993) - 1 Jan 2000
Shyrobokov V P, Kostenko I H, Nikolaienko I V
Abstract excerpt
Hybridomes--producers of monoclonal antibodies (MAB) were obtained able to differentiate the variants Abent+ and Abent- poliovirus vaccine strain in the virus neutralizing reaction. Using the obtained panel the changes of the epitope structure of capsid proteins of poliovirus variants (dissociants) were found which appeared during reproduction in cell culture. It proves the fact that there exist essential...
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