Characterization of a natural mutation in an antigenic site on the fusion protein of measles virus that is involved in neutralization.

doi:10.1128/JVI.73.1.787-790.1999

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Article

Characterization of a natural mutation in an antigenic site on the fusion protein of measles virus that is involved in neutralization.

Journal of virology - 1 Jan 1999

Fayolle J, Verrier B, Buckland R, Wild T F

Abstract excerpt

Although measles virus is an antigenically monotypic virus, nucleotide sequence analysis of the hemagglutinin and nucleoprotein genes has permitted the differentiation of a number of genotypes. In contrast, the fusion (F) protein is highly conserved; only three amino acid changes have been report...

Topics

Antibodies, Monoclonal
Antigens, Viral
Humans
Measles Vaccine
Measles virus
Mutation
Structure-Activity Relationship
Viral Fusion Proteins

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