Article
Improved association analyses of disease subtypes in case-parent triads.
Genetic epidemiology - 1 Apr 2006
Epstein Michael P, Waldman Irwin D, Satten Glen A
Abstract excerpt
The sampling of case-parent triads is an appealing strategy for conducting association analyses of complex diseases. In certain situations, one may have interest in using the triads to identify genetic variants that are associated with a specific subtype of disease, perhaps related to a characteristic cluster of symptoms. A straightforward strategy for conducting such a subtype analysis would be to analyze only...
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