Article
Contribution of NZB autoimmunity 2 to Y-linked autoimmune acceleration-induced monocytosis in association with murine systemic lupus.
Journal of immunology (Baltimore, Md. : 1950) - 1 Mar 2006
Kikuchi Shuichi, Santiago-Raber Marie-Laure, Amano Hirofumi, Amano Eri, Fossati-Jimack Liliane, Moll Thomas, Kotzin Brian L, Izui Shozo
Abstract excerpt
The accelerated development of systemic lupus erythematosus (SLE) in BXSB male mice is associated with the presence of the Y-linked autoimmune acceleration (Yaa) mutation, which induces an age-dependent monocytosis. Using a cohort of C57BL/6 (B6) x (NZB x B6)F1 backcross male mice bearing the Yaa...
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