Article
ARLTS1 variants and risk of colorectal cancer.
Cancer letters - 8 Dec 2006
Frank Bernd, Hemminki Kari, Brenner Hermann, Hoffmeister Michael, Chang-Claude Jenny, Burwinkel Barbara
Abstract excerpt
The Cys148Arg and Trp149Stop variants in the tumour suppressor gene ARLTS1 predispose to familial breast cancer, suggesting that these variants might also contribute to colorectal carcinogenesis. As the first to evaluate the association between Cys148Arg and Trp149Stop and colorectal cancer (CRC)...
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