Article
Association of the ARLTS1 variants with familial ovarian cancer risk in China.
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society - 1 May 2009
Yang Xiao-Yun, Yu Hai, Xi Ming-Rong, Yang Kai-Xuan, Pan Xiao-Ling, Hu Ming, Peng Zhi-Lan
Abstract excerpt
ARLTS1 has been identified in chromosome 13q14 as a tumor suppressor gene of the adenosine diphosphate-ribosylation factor family with pro-apoptotic characteristics. The ARLTS1 mutation Trp149Stop and Cys148Arg have been shown to be associated with familial cancers, but limited information is ava...
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