Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association of the ARLTS1 Cys148Arg variant with familial breast cancer risk.

International journal of cancer - 15 May 2006

Frank Bernd, Hemminki Kari, Meindl Alfons, Wappenschmidt Barbara, Klaes Rüdiger, Schmutzler Rita K, Untch Michael, Bugert Peter, Bartram Claus R, Burwinkel Barbara

Abstract excerpt

Recently, ARLTS1 (ADP-ribosylation factor-like tumor suppressor gene 1) has been identified as a tumor suppressor gene, playing a major role in apoptotic signaling. The ARLTS1 Trp149Stop mutation has been shown to predispose to general familial cancer and high-risk familial breast cancer (BC), pr...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to ADP-Ribosylation Factors
Share to Aged, 80 and over
Share to Breast Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Case-Control Studies

Share to DNA Mutational Analysis

Share to Functional Laterality

Share to Odds Ratio

Share to Pedigree

Source

Identifiers

PMID: 16353159
DOI: 10.1002/ijc.21687

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16353159-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association of the ARLTS1 Cys148Arg variant with familial breast cancer risk.PMID 16353159Read ↗

Association of the ARLTS1 Cys148Arg variant with sporadic and familial colorectal cancer.Semantic proximity Read ↗

Association of the ARLTS1 variants with familial ovarian cancer risk in China.Semantic proximity Read ↗

ARLTS1 variants and melanoma risk.Semantic proximity Read ↗

ARLTS1 germline variants and the risk for breast, prostate, and colorectal cancer.Semantic proximity Read ↗

Contribution of ARLTS1 Cys148Arg (T442C) variant with prostate cancer risk and ARLTS1 function in prostate cancer cells.Semantic proximity Read ↗

ARLTS1 variants and risk of colorectal cancer.Semantic proximity Read ↗

ARLTS1, potential candidate gene in familial aggregation of hematological malignancies.Semantic proximity Read ↗

Familial Cancer Associated with a Polymorphism in<i>ARLTS1</i>Semantic proximity Read ↗

Familial cancer associated with a polymorphism in ARLTS1.Semantic proximity Read ↗

Cancer Familial Aggregation (CFA) and G446A polymorphism in ARLTS1 gene.Semantic proximity Read ↗

The BARD1 Cys557Ser variant and risk of familial breast cancer in a South-American population.Semantic proximity Read ↗

An intronic polymorphism associated with increased XRCC1 expression, reduced apoptosis and familial breast cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.