Article
Association of the ARLTS1 Cys148Arg variant with sporadic and familial colorectal cancer.
Carcinogenesis - 1 Aug 2007
Castellví-Bel Sergi, Castells Antoni, de Cid Rafael, Muñoz Jenifer, Balaguer Francesc, Gonzalo Victoria, Ruiz-Ponte Clara, Andreu Montserrat, Llor Xavier, Jover Rodrigo, Bessa Xavier, Xicola Rosa M, Pons Elisenda, Alenda Cristina, Payá Artemio, Carracedo Angel, Piqué Josep M
Abstract excerpt
ARLTS1 was recently identified in chromosome 13q14 as a tumor suppressor gene of the ADP-ribosylation factor family with pro-apoptotic characteristics. Additionally, one of its genetic variants (W149X) was hypothesized to be a polymorphism associated with familial cancer. We performed a large cas...
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