Article
Interaction between COX-1 and COX-2 increases susceptibility to ischemic stroke in a Chinese population.
BMC neurology - 17 Nov 2019
Zhao Lei, Fang Jinghuan, Zhou Muke, Zhou Jie, Yu Lihua, Chen Ning, He Li
Abstract excerpt
BACKGROUND: Mutations of cyclooxygenase gene (COX gene) may increase the susceptibility of ischemic stroke. We investigated five variants (rs5788, rs1330344, rs3842788, rs20417, and rs689466) of two COX genes in order to explaining the association between these polymorphisms and we also investigated the association between these variants and ischemic stroke risk to determine whether gene-gene interaction between...
