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Article

Estrogen and progesterone receptor gene polymorphisms and sporadic breast cancer risk: a Spanish case-control study.

International journal of cancer - 15 Jul 2006

Fernández L P, Milne R L, Barroso E, Cuadros M, Arias J I, Ruibal A, Benítez J, Ribas G

Abstract excerpt

Estrogens, and to a lesser extent progesterones, influence the proliferation, differentiation and physiology of breast tissue as well as the development and progression of breast cancer. Genetic variants in the steroid hormone receptor genes ESR1 and PGR (belonging to the nuclear receptor superfamily) could therefore modify sporadic breast cancer susceptibility. Two studies have shown a protective effect...

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Source

Identifiers

PMID: 16477637
DOI: 10.1002/ijc.21847

Genes

ESR1
PGR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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