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Article

Variants of estrogen receptor alpha and beta genes modify the severity of sporadic breast cancer.

Gene - 15 Apr 2017

Rezende Luciana Montes, Marson Fernando Augusto Lima, Lima Carmen Sílvia Passos, Bertuzzo Carmen Sílvia

Abstract excerpt

INTRODUCTION: Reproductive factors pose a risk for sporadic breast cancer (BC) development owing to the lifetime exposure to estrogen, a hormone responsible for cell proliferation in the breast. Because variants of the estrogen receptor (ER) alpha and beta genes have been associated with BC risk in numerous populations, the objective of the study was to determine whether the risk and severity of sporadic BC was...

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Source

Identifiers

PMID: 28109853
DOI: 10.1016/j.gene.2017.01.010

Genes

ESR1
ESR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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