p53 point mutation in HPV negative human cervical carcinoma cell lines.

Article

p53 point mutation in HPV negative human cervical carcinoma cell lines.

Oncogene - 1 May 1991

Crook T, Wrede D, Vousden K H

Abstract excerpt

Clinical and experimental evidence is consistent with a key role for transforming human papilloma viruses (HPVs) in the aetiology of anogenital carcinoma. Cervical carcinoma does, however, occasionally occur in the absence of HPV sequences (Riou et al., 1990). We have used a direct cDNA/PCR seque...

Topics

Base Sequence
Cell Line
Female
Humans
Molecular Sequence Data
Mutation
Oligonucleotide Probes
Papillomaviridae
Polymerase Chain Reaction
Tumor Suppressor Protein p53
Uterine Cervical Neoplasms

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