Article
Serrated polyposis associated with a family history of colorectal cancer and/or polyps: The preferential location of polyps in the colon and rectum defines two molecular entities.
International journal of molecular medicine - 1 Sept 2016
Silva Patrícia, Albuquerque Cristina, Lage Pedro, Fontes Vanessa, Fonseca Ricardo, Vitoriano Inês, Filipe Bruno, Rodrigues Paula, Moita Susana, Ferreira Sara, Sousa Rita, Claro Isabel, Nobre Leitão Carlos, Chaves Paula, Dias Pereira António
Abstract excerpt
Serrated polyposis (SPP) is characterized by the development of multiple serrated polyps and an increased predisposition to colorectal cancer (CRC). In the present study, we aimed to characterize, at a clinical and molecular level, a cohort of SPP patients with or without a family history of SPP and/or polyps/CRC (SPP-FHP/CRC). Sixty-two lesions from 12 patients with SPP-FHP/CRC and 6 patients with sporadic SPP...
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