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Article

Concordant CpG island methylation in hyperplastic polyposis.

The American journal of pathology - 1 Feb 2002

Chan Annie On-On, Issa Jean-Pierre J, Morris Jeffrey S, Hamilton Stanley R, Rashid Asif

Abstract excerpt

The CpG island methylator phenotype (CIMP) is a newly described mechanism for carcinogenesis in colorectal carcinomas and adenomas characterized by methylation of multiple CpG islands. The causes of CIMP are unknown. We studied CIMP in hyperplastic polyps (HPs), with emphasis on patients with multiple HPs (5 to 10 HPs), large HPs (one HP >1 cm) or hyperplastic polyposis (>20 HPs). Methylation of p16, MINT1,...

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Identifiers

PMID: 11839573
DOI: 10.1016/S0002-9440(10)64872-9
PMCID: PMC1850645

Genes

HP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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