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Article

Methylation patterns define two types of hyperplastic polyp associated with colorectal cancer.

Gut - 1 Apr 2004

Wynter C V A, Walsh M D, Higuchi T, Leggett B A, Young J, Jass J R

Abstract excerpt

AIM: Hyperplastic polyps (HP) of the colorectum have traditionally been regarded as non-neoplastic lesions. Recent data implicate HP in the pathogenesis of colorectal cancers (CRC) characterised by extensive DNA methylation and microsatellite instability. The aim of this study was to identify morphological and molecular features that may characterise subtypes of HP with potential for neoplastic progression....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 15016754
DOI: 10.1136/gut.2003.030841
PMCID: PMC1774017

Genes

MGMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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