Article
Yeast nuclear envelope subdomains with distinct abilities to resist membrane expansion.
Molecular biology of the cell - 1 Apr 2006
Campbell Joseph L, Lorenz Alexander, Witkin Keren L, Hays Thomas, Loidl Josef, Cohen-Fix Orna
Abstract excerpt
Little is known about what dictates the round shape of the yeast Saccharomyces cerevisiae nucleus. In spo7Delta mutants, the nucleus is misshapen, exhibiting a single protrusion. The Spo7 protein is part of a phosphatase complex that represses phospholipid biosynthesis. Here, we report that the nuclear protrusion of spo7Delta mutants colocalizes with the nucleolus, whereas the nuclear compartment containing the...
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