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Article

Nuclear shape, growth and integrity in the closed mitosis of fission yeast depend on the Ran-GTPase system, the spindle pole body and the endoplasmic reticulum.

Journal of cell science - 15 Jul 2009

Gonzalez Yanira, Meerbrey Kristen, Chong Jennifer, Torii Yoshihiro, Padte Neal N, Sazer Shelley

Abstract excerpt

The double lipid bilayer of the nuclear envelope (NE) remains intact during closed mitosis. In the fission yeast Schizosaccharomyces pombe, the intranuclear mitotic spindle has envelope-embedded spindle pole bodies (SPB) at its ends. As the spindle elongates and the nucleus divides symmetrically, nuclear volume remains constant but nuclear area rapidly increases by 26%. When Ran-GTPase function is compromised in...

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Identifiers

PMID: 19571115
DOI: 10.1242/jcs.049999
PMCID: PMC2704881

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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