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Article

Nuclear size control in fission yeast.

The Journal of cell biology - 19 Nov 2007

Neumann Frank R, Nurse Paul

Abstract excerpt

A long-standing biological question is how a eukaryotic cell controls the size of its nucleus. We report here that in fission yeast, nuclear size is proportional to cell size over a 35-fold range, and use mutants to show that a 16-fold change in nuclear DNA content does not influence the relative size of the nucleus. Multi-nucleated cells with unevenly distributed nuclei reveal that nuclei surrounded by a greater...

Topics

Biomarkers
Cell Cycle Proteins
Cell Nucleus
Cell Size
Cytoplasm
Fluorescent Dyes
Green Fluorescent Proteins
Indoles
Microscopy, Video
Mutation
Nuclear Proteins
Organelle Size

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Schizosaccharomyces

Schizosaccharomyces pombe Proteins

Temperature

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Identifiers

PMID: 17998401
DOI: 10.1083/jcb.200708054
PMCID: PMC2080919

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