Article
Members of the RSC chromatin-remodeling complex are required for maintaining proper nuclear envelope structure and pore complex localization.
Molecular biology of the cell - 15 Mar 2010
Titus Laura C, Dawson T Renee, Rexer Deborah J, Ryan Kathryn J, Wente Susan R
Abstract excerpt
The assembly, distribution, and functional integrity of nuclear pore complexes (NPCs) in the nuclear envelope (NE) are key determinants in the nuclear periphery architecture. However, the mechanisms controlling proper NPC and NE structure are not fully defined. We used two different genetic screening approaches to identify Saccharomyces cerevisiae mutants with defects in NPC localization. The first approach...
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