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Article

Approaches to studying subnuclear organization and gene-nuclear pore interactions.

Methods in cell biology - 1 Jan 2014

Egecioglu Defne Emel, D'Urso Agustina, Brickner Donna Garvey, Light William H, Brickner Jason H

Abstract excerpt

Many genes in budding yeast Saccharomyces cerevisiae associate with the nuclear pore complex (NPC), which impacts their location within the nucleus and their transcriptional regulation. To understand how eukaryotic genomes are spatially organized, we have used multiple approaches for analyzing the localization and transcription of genes. We have used these approaches to study the role of DNA elements in targeting...

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PMID: 24857743
DOI: 10.1016/B978-0-12-417160-2.00021-7
PMCID: PMC4697751

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Source receipt: pubmed, retrieved 7 Sept 2026.

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