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Article

The GNAS1 T393C polymorphism predicts survival in patients with clear cell renal cell carcinoma.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Feb 2006

Frey Ulrich H, Lümmen Gerd, Jäger Tobias, Jöckel Karl-Heinz, Schmid Kurt W, Rübben Herbert, Müller Norbert, Siffert Winfried, Eisenhardt Andreas

Abstract excerpt

PURPOSE: G proteins mediate signaling from cell surface receptors to specific intracellular proteins. In vitro cancer cell line studies revealed a link between the Galphas protein and proapoptotic processes. We have recently shown that TT genotypes of the GNAS1 T393C polymorphism display increased transcription of Galphas and a more favorable clinical course in bladder and colorectal cancer patients compared both...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 16467086
DOI: 10.1158/1078-0432.CCR-05-1722

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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