Article
Association of RASSF1A genotype and haplotype with the progression of clear cell renal cell carcinoma in Japanese patients.
BJU international - 1 Oct 2012
Kawai Yoshihisa, Sakano Shigeru, Okayama Naoko, Suehiro Yutaka, Matsuyama Hideyasu, Hinoda Yuji
Abstract excerpt
UNLABELLED: What's known on the subject? and What does the study add? Ras association domain family 1A (RASSF1A) is a tumour suppressor and regulates cell cycle, apoptosis and microtubule stability. This is the first study to identify associations between RASSF1A polymorphisms and clinicopathological parameters and survival in patients with clear cell renal cell carcinoma (CCRCC). RASSF1A genotyping may be useful...
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