Article
Progressive loss of echinocandin activity following prolonged use for treatment of Candida albicans oesophagitis
7 Feb 2006
Abstract excerpt
OBJECTIVES: To illustrate the progressive loss of cross-echinocandin activity on Candida albicans isolates with strong clonal homology from a patient with advanced HIV infection and chronic oesophagitis progressively resistant to uninterrupted micafungin treatment. METHODS: Antifungal susceptibility profiles for different antifungal agents were determined against serial C. albicans isolates retrieved before and...
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