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Article

Rapid emergence of echinocandin resistance in Candida glabrata resulting in clinical and microbiologic failure.

Antimicrobial agents and chemotherapy - 1 Sept 2013

Lewis James S, Wiederhold Nathan P, Wickes Brian L, Patterson Thomas F, Jorgensen James H

Abstract excerpt

We report a case of Candida glabrata candidemia that developed resistance to micafungin within 8 days of initiation of therapy in a patient without previous echinocandin exposure or other known risk factors for clinical or microbiological failure. Pre- and postresistant isolates were confirmed to be isogenic, and sequencing of hot spots known to confer echinocandin resistance revealed a phenylalanine deletion at...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 23817368
DOI: 10.1128/AAC.01144-13
PMCID: PMC3754289

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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