Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Characterization of In Vitro Resistance Development to the Novel Echinocandin CD101 in Candida Species.

Antimicrobial agents and chemotherapy - 1 Oct 2016

Locke Jeffrey B, Almaguer Amanda L, Zuill Douglas E, Bartizal Ken

Abstract excerpt

CD101 is a novel echinocandin with a long half-life undergoing clinical development for treatment of candidemia/invasive candidiasis and vulvovaginal candidiasis. The potential for and mechanisms underlying the development of resistance to CD101 in Candida species were investigated by using spontaneous resistance and serial passage selection methodologies. Four Candida spp. (C. albicans, C. glabrata, C....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antifungal Agents
Share to Candida
Share to Candida albicans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Candida glabrata

Share to Caspofungin

Share to Drug Resistance, Fungal

Share to Echinocandins

Share to Lipopeptides

Source

Open in PubMed Open full text

Identifiers

PMID: 27480852
DOI: 10.1128/AAC.00620-16
PMCID: PMC5038289

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Characterization of In Vitro Resistance Development to the Novel Echinocandin CD101 in Candida Species.PMID 27480852Read ↗

Echinocandin Resistance in Candida.Semantic proximity Read ↗

Resistance to echinocandin-class antifungal drugs.Semantic proximity Read ↗

Global Analysis of the Evolution and Mechanism of Echinocandin Resistance in Candida glabrataSemantic proximity Read ↗

Echinocandin resistance: an emerging clinical problem?Semantic proximity Read ↗

Candida parapsilosis isolates carrying mutations outside FKS1 hotspot regions confer high echinocandin tolerance and facilitate the development of echinocandin resistance.Semantic proximity Read ↗

FKS1 mutation associated with decreased echinocandin susceptibility of Aspergillus fumigatus following anidulafungin exposure.Semantic proximity Read ↗

In Vivo Evolution of Candida auris Multidrug Resistance in a Patient Receiving Antifungal Treatment.Semantic proximity Read ↗

Development of Echinocandin Resistance in Candida haemulonii: An Emergent, Widespread, and Opportunistic Fungal PathogenSemantic proximity Read ↗

Antifungal drug resistance mechanisms.Semantic proximity Read ↗

Clinical perspectives on echinocandin resistance among Candida species.Semantic proximity Read ↗

Evolutionary accumulation of FKS1 mutations from clinical echinocandin-resistant Candida auris.Semantic proximity Read ↗

Fungal Resistance to Echinocandins and the MDR Phenomenon in Candida glabrataSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.