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Article

Rapid emergence of echinocandin resistance during Candida kefyr fungemia treatment with caspofungin.

Antimicrobial agents and chemotherapy - 1 May 2013

Fekkar A, Meyer I, Brossas J Y, Dannaoui E, Palous M, Uzunov M, Nguyen S, Leblond V, Mazier D, Datry A

Abstract excerpt

Echinocandin drugs are widely used for the treatment of candidemia. Resistance is considered rare, and only a few cases of breakthrough candidiasis in patients receiving echinocandin have been reported worldwide. We report here for the first time a Candida kefyr isolate that acquired echinocandin resistance very rapidly after the initiation of caspofungin treatment for candidemia. We characterized the FKS gene...

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Identifiers

PMID: 23439642
DOI: 10.1128/AAC.02037-12
PMCID: PMC3632960

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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