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Article

Mismatch repair, p53 and chromosomal aberrations in primary colorectal carcinomas.

Acta oncologica (Stockholm, Sweden) - 1 Jan 2006

Mehigan Brian J, Ashman James N E, Baker Richard P, Macdonald Alastair, Greenman John, Monson John R T, Cawkwell Lynn

Abstract excerpt

Colorectal carcinoma progresses via at least two genetic pathways. Microsatellite instability, due to defective mismatch repair genes, characterizes one pathway and gross chromosomal instability another. The involvement of p53 and mismatch repair gene abnormalities within these pathways has not b...

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Share to Adaptor Proteins, Signal Transducing
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16464797
DOI: 10.1080/02841860500374463

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16464797-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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