Article
Distinctive patterns of p53 protein expression and microsatellite instability in human colorectal cancer.
Human pathology - 1 Dec 2011
Nyiraneza Christine, Jouret-Mourin Anne, Kartheuser Alex, Camby Philippe, Plomteux Olivier, Detry Roger, Dahan Karin, Sempoux Christine
Abstract excerpt
Although evidence suggests an inverse relationship between microsatellite instability and p53 alterations in colorectal cancer, no study has thoroughly examined the use of p53 immunohistochemistry in phenotyping colorectal cancers. We investigated the value of p53 immunohistochemistry in microsatellite instability-positive colorectal cancers prescreening and attempted to clarify the relationship between DNA...
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