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Article

TP53 status and gene amplification in human colorectal carcinomas.

Cancer genetics and cytogenetics - 1 Dec 1999

Soulié P, Fourme E, Hamelin R, Asselain B, Salmon R J, Dutrillaux B, Muleris M

Abstract excerpt

Gene amplification is one of the characteristics of cancer cells. In vitro studies suggested that alterations of the TP53 gene might be responsible for gene amplification. We have examined the presence of TP53 mutations and looked for cytogenetic evidence of gene amplification in a series of 79 primary colorectal carcinomas. Other parameters such as the pattern of cytogenetic alterations, microsatellite...

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Identifiers

PMID: 10598144
DOI: 10.1016/s0165-4608(99)00073-4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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