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Article

Loss of hMSH2 expression in primary breast cancer with p53 alterations.

Oncology reports - 1 Apr 2004

Spagnoletti Ilaria, Pizzi Claudia, Galietta Annamaria, Di Maio Massimo, Mastranzo Paolo, Daniele Santa, Limite Gennaro, Pettinato Guido, Contegiacomo Alma

Abstract excerpt

Inactivation of DNA mismatch repair genes (MRG) is a recently described pathway of cancer development and progression resulting in genetic instability. Germline mutations in MRG have been studied predominantly in patients with hereditary non-polyposis colorectal cancer (HNPCC) where it is associated with microsatellite instability (MSI). The expression of MRG in primary breast cancer is still largely unexplored....

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Share to Colorectal Neoplasms, Hereditary Nonpolyposis
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genes, p53

Share to Immunochemistry

Share to MutS Homolog 2 Protein

Share to Proto-Oncogene Proteins

Share to Receptor, ErbB-2

Share to Tumor Suppressor Protein p53

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Identifiers

PMID: 15010883

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Loss of hMSH2 expression in primary breast cancer with p53 alterations.PMID 15010883Read ↗

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