Article
Poly(ADP-ribose) polymerase (PARP) polymorphisms associated with nephritis and arthritis in systemic lupus erythematosus.
Rheumatology (Oxford, England) - 1 Jun 2006
Hur J-W, Sung Y-K, Shin H D, Park B L, Cheong H S, Bae S-C
Abstract excerpt
OBJECTIVE: The objective of this study was to confirm whether polymorphisms of the poly(ADP-ribose) polymerase gene (PARP) are associated with genetic susceptibility to systemic lupus erythematosus (SLE) and to investigate the possible association of nephritis and arthritis in SLE with PARP polymorphisms. METHODS: Using direct DNA sequencing in 24 individuals, we identified 44 sequence variants within exons and...
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