Article
Association between severe disease course and nephritis with Q222R polymorphism in DNAse I gene among lupus patients: An Argentine multicenter study.
Acta reumatologica portuguesa - 1 Jan 2000
Camicia G, Muñoz S A, Allievi A, Orden A O, Perés Wingeyer S, Trobo R, Eimon A, Barreira J C, Schneeberger E, Sarano J, Hofman J, de Larrañaga G, Aranda F
Abstract excerpt
UNLABELLED: Objetives: Systemic lupus erythematosus is a multifactorial autoimmune disease and the glomerulonephritis is one of the most severe complications, which leads to severe persistent proteinuria, chronic renal failure, and end-stage renal disease. This multicenter study investigated the genetic associations of a non-synonymous single-nucleotide polymorphism in DNase I with the risk of lupus and its...
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