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Article

Common DNase I polymorphism associated with autoantibody production among systemic lupus erythematosus patients.

Human molecular genetics - 15 Oct 2004

Shin Hyoung Doo, Park Byung Lae, Kim Lyoung Hyo, Lee Hye-Soon, Kim Think-You, Bae Sang-Cheol

Abstract excerpt

DNase I could be the most important nuclease for the removal of DNA from nuclear antigens at sites of high cell turnover, and thus may also prevent systemic lupus erythematosus (SLE). Sixteen SNPs were identified by direct DNA sequencing, among which six were selected for genotyping in a larger investigation on the basis of linkage disequilibria among SNPs, their frequency, location and haplotype tagging status....

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Identifiers

PMID: 15333586
DOI: 10.1093/hmg/ddh275

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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