Article
DNase II polymorphisms associated with risk of renal disorder among systemic lupus erythematosus patients.
Journal of human genetics - 1 Jan 2005
Shin Hyoung Doo, Park Byung Lae, Cheong Hyun Sup, Lee Hye-Soon, Jun Jae-Bum, Bae Sang-Cheol
Abstract excerpt
DNase II is an important enzyme for DNA fragmentation and degradation during programmed cell death and, consequently, a potential candidate gene for genetic study of systemic lupus erythematosus (SLE). Genetic associations of DNase II with SLE and related phenotypes were examined in Korean patients with SLE. A total of 350 Korean SLE patients and 330 healthy subjects were enrolled. Direct DNA sequencing and...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
