Article
Rs4948496 within ARID5B gene is associated with clinical features of systemic lupus erythematosus in the Chinese Han population.
The Journal of dermatology - 1 Jun 2015
Jiang Long, Wu Jianping, Li Weiran, Du Juan, Wang Wenjun, Zhu Zhengwei, Gao Jinping, Sheng Yujun, Yin Xianyong, Zheng Xiaodong, Li Hui, Li Yang, Meng Li, Fan Xing, Liu Shengxiu, Zeng Ming, Wang Zaixing, Cui Yong, Tang Huayang, Sun Liangdan, Yang Sen, Zhang Xuejun
Abstract excerpt
In our previous meta-analysis of genome-wide association study, we identified the single nucleotide polymorphism (SNP) rs4948496 (P = 5.1 × 10(-11) , odds ratio [OR] = 0.85) within the ARID5B gene associated with systemic lupus erythematosus (SLE) in a Chinese population. To investigate its association with disease subphenotypes, we further analyzed the genotype data of rs4948496 in 4348 cases and 6679 controls...
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