Article
Multiplex PCR-RFLP methods for pfcrt, pfmdr1 and pfdhfr mutations in Plasmodium falciparum.
Molecular and cellular probes - 1 Apr 2006
Veiga Maria Isabel, Ferreira Pedro Eduardo, Björkman Anders, Gil José Pedro
Abstract excerpt
Plasmodium falciparum drug resistance is a major factor for the death toll of malaria. Resistance has been associated with specific single nucleotide polymorphisms (SNPs) in the parasite genes pfmdr1 (N86Y) and pfcrt (K76T) associated with quionoline antimalarial resistance, and pfdhfr (N51I, C59...
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