Article
Multiplex PCR and oligonucleotide microarray for detection of single-nucleotide polymorphisms associated with Plasmodium falciparum drug resistance.
Journal of clinical microbiology - 1 Jul 2008
Zhang Guo Qing, Guan Ya Yi, Sheng Hai Hui, Zheng Bin, Wu Song, Xiao Hua Sheng, Tang Lin Hua
Abstract excerpt
Drug resistance in Plasmodium falciparum is a serious public health threat in the countries where this organism is endemic. Since resistance has been associated with specific single-nucleotide polymorphisms (SNPs) in parasite genes, molecular markers are becoming useful surrogates for monitoring...
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