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Article

Molecular surveillance of antimalarial drug resistance markers in the pfcrt, pfmdr1 and pfmrp1 genes of Plasmodium falciparum isolates from southeastern Iran.

Malaria journal - 19 Jun 2026

Jafari Mohadeseh, Rezapour Romina, Nemati Fahimeh, Mehrizi Akram Abouie, Pirahmadi Sakineh

Abstract excerpt

BACKGROUND: The emergence and spread of Plasmodium falciparum resistance to artemisinin and its partner drugs pose a major challenge to malaria elimination efforts. Continuous monitoring of resistance-associated molecular markers provides valuable insights into the emergence of resistant genotypes and their geographical distribution. METHODS: In this study, we investigated mutations linked to antimalarial drug...

Read the complete abstract on PubMed

Topics

Plasmodium falciparum
Protozoan Proteins
ATP-Binding Cassette, Sub-Family C Proteins
Iran
Antimalarials
Drug Resistance

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Membrane Transport Proteins

Humans

Malaria, Falciparum

Polymorphism, Restriction Fragment Length

Genotype

Polymerase Chain Reaction

Source

Open in PubMed Open full text

Identifiers

PMID: 42321796
DOI: 10.1186/s12936-026-06012-w
PMCID: PMC13536877

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