Article
Molecular assessment of Plasmodium falciparum resistance to antimalarial drugs in Papua New Guinea using an extended ligase detection reaction fluorescent microsphere assay.
Antimicrobial agents and chemotherapy - 1 Feb 2011
Wong Rina P M, Karunajeewa Harin, Mueller Ivo, Siba Peter, Zimmerman Peter A, Davis Timothy M E
Abstract excerpt
Surveillance for Plasmodium falciparum drug resistance mutations is becoming an established tool for assessing antimalarial treatment effectiveness. We used an extended version of a high-throughput post-PCR multiplexed ligase detection reaction fluorescent microsphere assay (LDR-FMA) to detect single-nucleotide P. falciparum drug resistance polymorphisms in 402 isolates from children in Papua New Guinea (PNG)...
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