Article
Rapid microarray-based method for monitoring of all currently known single-nucleotide polymorphisms associated with parasite resistance to antimalaria drugs.
Journal of clinical microbiology - 1 Nov 2007
Crameri Andreas, Marfurt Jutta, Mugittu Kefas, Maire Nicolas, Regös Attila, Coppee Jean Yves, Sismeiro Odile, Burki Richard, Huber Eric, Laubscher Daniel, Puijalon Odile, Genton Blaise, Felger Ingrid, Beck Hans-Peter
Abstract excerpt
Parasite drug resistance is partly conferred by single-nucleotide polymorphisms (SNPs), and monitoring them has been proposed as an alternative to monitoring drug resistance. Therefore, techniques are required to facilitate analyses of multiple SNPs on an epidemiological scale. We report a rapid and affordable microarray technique for application in epidemiological studies of malaria drug resistance. We have...
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