Article
Variation in 24 hemostatic genes and associations with non-fatal myocardial infarction and ischemic stroke.
Journal of thrombosis and haemostasis : JTH - 1 Jan 2008
Smith N L, Bis J C, Biagiotti S, Rice K, Lumley T, Kooperberg C, Wiggins K L, Heckbert S R, Psaty B M
Abstract excerpt
BACKGROUND: Arterial thrombosis involves platelet aggregation and clot formation, yet little is known about the contribution of genetic variation in fibrin-based hemostatic factors to arterial clotting risk. We hypothesized that common variation in 24 coagulation-fibrinolysis genes would contribute to risk of incident myocardial infarction (MI) or ischemic stroke (IS). METHODS: We conducted a population-based,...
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