Article
Thrombomodulin gene polymorphisms in brain infarction and mortality after stroke.
Journal of neurology - 1 Apr 2008
Olivot Jean-Marc, Labreuche Julien, De Broucker Thomas, Poirier Odette, Cambien François, Aiach Martine, Amarenco Pierre
Abstract excerpt
BACKGROUND AND PURPOSE: Thrombomodulin is expressed at the surface of endothelial cells and controls thrombin generation and thrombin-induced platelets and vascular cell activation. Several thrombomodulin gene polymorphisms have been associated with coronary events and brain infarction. In a previous analysis from the Etude du Profil Génétique de l'Infarctus Cérébral (GENIC) study, we found that soluble...
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