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Article

Thrombomodulin gene mutations associated with myocardial infarction.

Circulation - 1 Jul 1997

Ireland H, Kunz G, Kyriakoulis K, Stubbs P J, Lane D A

Abstract excerpt

BACKGROUND: Thrombomodulin is an important receptor for thrombin on the endothelial cell surface of most blood vessels, including those of the heart. Thrombin-bound thrombomodulin activates protein C, which inhibits thrombin generation by degrading factors Va and VIIIa. The aim of this study was...

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Source

Identifiers

PMID: 9236408
DOI: 10.1161/01.cir.96.1.15

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-9236408-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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