No evidence of association between prothrombotic gene polymorphisms and the development of acute myocardial infarction at a young age.

Abstract excerpt

BACKGROUND: We investigated the association between 9 polymorphisms of genes encoding hemostasis factors and myocardial infarction in a large sample of young patients chosen because they have less coronary atherosclerosis than older patients, and thus their disease is more likely to be related to a genetic predisposition to a prothrombotic state. METHODS AND RESULTS: This nationwide case-control study involved...

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