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Article

Signal dynamics in Sonic hedgehog tissue patterning.

Development (Cambridge, England) - 1 Mar 2006

Saha Krishanu, Schaffer David V

Abstract excerpt

During development, secreted signaling factors, called morphogens, instruct cells to adopt specific mature phenotypes. However, the mechanisms that morphogen systems employ to establish a precise concentration gradient for patterning tissue architecture are highly complex and are typically analyzed only at long times after secretion (i.e. steady state). We have developed a theoretical model that analyzes...

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Identifiers

PMID: 16452094
DOI: 10.1242/dev.02254

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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