Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A Hedgehog activity gradient contributes to AP axial patterning of the Drosophila wing.

Development (Cambridge, England) - 1 Nov 1997

Strigini M, Cohen S M

Abstract excerpt

The secreted protein Hedgehog (Hh) transmits a signal from posterior to anterior cells that is essential for limb development in insects and vertebrates. In Drosophila, Hh has been thought to act primarily to induce localized expression of Decapentaplegic and Wingless which in turn relay patterning cues at long range. We report here that Hh plays an additional role in patterning the wing. By replacing endogenous...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Drosophila
Share to Drosophila Proteins
Share to Gene Expression Regulation, Developmental

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genes, Insect

Share to Insect Proteins

Share to Membrane Proteins

Share to Mutation

Share to Signal Transduction

Source

Identifiers

PMID: 9409685
DOI: 10.1242/dev.124.22.4697

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A Hedgehog activity gradient contributes to AP axial patterning of the Drosophila wing.PMID 9409685Read ↗

Induction of a mirror-image duplication of anterior wing structures by localized hedgehog expression in the anterior compartment of Drosophila melanogaster wing imaginal discs.Semantic proximity Read ↗

The Drosophila hedgehog gene is expressed specifically in posterior compartment cells and is a target of engrailed regulation.Semantic proximity Read ↗

Notch and Wingless modulate the response of cells to Hedgehog signalling in the Drosophila wing.Semantic proximity Read ↗

Hedgehog is an indirect regulator of morphogenetic furrow progression in the Drosophila eye disc.Semantic proximity Read ↗

slimb coordinates wg and dpp expression in the dorsal-ventral and anterior-posterior axes during limb development.Semantic proximity Read ↗

Positional signaling by hedgehog in Drosophila imaginal disc development.Semantic proximity Read ↗

Differential requirements of the fused kinase for hedgehog signalling in the Drosophila embryo.Semantic proximity Read ↗

Distinct pathways for autocrine and paracrine Wingless signalling in Drosophila embryos.Semantic proximity Read ↗

Targeted expression of the signaling molecule decapentaplegic induces pattern duplications and growth alterations in Drosophila wings.Semantic proximity Read ↗

Dispatched mediates Hedgehog basolateral release to form the long-range morphogenetic gradient in the Drosophila wing disk epithelium.Semantic proximity Read ↗

Specification of the wing by localized expression of wingless protein.Semantic proximity Read ↗

The hedgehog signaling network.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.