Article
A Hedgehog activity gradient contributes to AP axial patterning of the Drosophila wing.
Development (Cambridge, England) - 1 Nov 1997
Strigini M, Cohen S M
Abstract excerpt
The secreted protein Hedgehog (Hh) transmits a signal from posterior to anterior cells that is essential for limb development in insects and vertebrates. In Drosophila, Hh has been thought to act primarily to induce localized expression of Decapentaplegic and Wingless which in turn relay patterni...
Topics
- Animals
- Animals, Genetically Modified
- Drosophila
- Drosophila Proteins
- Gene Expression Regulation, Developmental
- Genes, Insect
- Hedgehog Proteins
- Insect Proteins
- Membrane Proteins
- Mutation
- Signal Transduction
- Wings, Animal