Article
The effect that genotyping errors have on the robustness of common linkage-disequilibrium measures.
American journal of human genetics - 1 Jun 2001
Akey J M, Zhang K, Xiong M, Doris P, Jin L
Abstract excerpt
The rapid development of a dense single-nucleotide-polymorphism marker map has stimulated numerous studies attempting to characterize the magnitude and distribution of background linkage disequilibrium (LD) within and between human populations. Although genotyping errors are an inherent problem in all LD studies, there have been few systematic investigations documenting their consequences on estimates of...
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